Since looking at data through an in-circuit emulator debug interface is generally a miserable experience, getting serial data communication with a custom PC application is essential to analyzing data quality and providing feedback on hardware designs. Mostly USB virtual serial posts from FTDI, but also the USB Communication Device Class and real 16550-compatible UARTs on the PCI bus.
As an embedded developer who writes desktop software mostly for configuration of, and data download from, peripheral devices, I use serial data streams a lot.
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